Genetic differences define severity of renal damage after L-NAME-induced hypertension in rats.
نویسندگان
چکیده
منابع مشابه
Blood pressure and the susceptibility to renal damage after unilateral nephrectomy and L-NAME-induced hypertension in rats.
BACKGROUND Fawn-hooded hypertensive (FHH) rats carry several genes which determine the susceptibility to develop renal damage, while renal damage resistant August x Copenhagen Irish (ACI) rats do not. Kidneys from heterozygous (FHH x ACI) F(1) rats, appear to be largely, but not completely, protected after blood pressure elevation with N(omega)-nitro-L-arginine methyl ester (L-NAME). We examine...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1998
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v93363